TOEFL READING PRACTICE WITH ANSWERS
TOEFL 14 (READING PASSAGE 5)
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Question
45-50
Elizabeth
Hazen and Rachel Brown copatented one of the most widely acclaimed wonder drugs
of the post-Second World War years. Hazen and Brown's work was stimulated
by the wartime need to find a cure for the fungus infections that afflicted
many military personnel. Scientists had been feverishly searching for an
antibiotic toxic enough to kill the fungi but safe enough for human use,
since, unfortunately, the new "wonder drugs" such as penicillin
and streptomycin killed the very bacteria in the body that controlled the
fungi. It was to discover a fungicide without that double effect that
Brown, of New York State's Department of Health Laboratories at Albany, and
Hazen, senior microbiologist at the Department of Health in New York, began
their long-distance collaboration. Based upon Hazen's previous research at
Columbia University, where she had built an impressive collection of fungus
cultures, both were convinced that an antifungal organism already existed
in certain soils.
They
divided the work. Hazen methodically screened and cultured scores of soil
samples, which she then sent to her partner, who prepared extracts,
isolated and purified active agents, and shipped them back to New York,
where Hazen could study their biological properties. On a 1948 vacation,
Hazen fortuitously collected a clump of soil from the edge of W.B. Nourse's
cow pasture, Hazen fortuitously collected a clump of soil from the edge of
W.B. Nourse's cow pasture in Fauquier County, Virginia, that, when tested,
revealed the presence of the microorganisms. In farm owner Nourse's honor.
Hazen named it Streptomyces noursei, and within a year the two scientists
knew that the properties of their substance distinguished it from
previously described antibiotics. After further research they eventually
reduced their substance to a fine, yellow powder, which they first named
"fungiciden." Then renamed "nystatin" (to honor the New
York State laboratory) when they learned the previous name was already in
use. Of their major discovery, Brown said lightly that it simply
illustrated "how unpredictable consequences can come from rather modest
beginnings."
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45
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What is the main topic of the passage?
(A) The lives of Hazen and Brown.
(B) The development of a safe fungicide.
(C) The New York State Department of Health.
(D) The development of penicillin.
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46
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What can be inferred
from the passage about penicillin?
(A) It effectively
treats fungus infections.
(B) It was developed
before nystatin.
(C) It was developed
before the Second World War.
(D) One of its
by-products is nystatin.
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47
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Why does the author mention Columbia University
in lines 10 and 11?
(A) Hazen and Brown developed nystatin there.
(B) Brown was educated there.
(C) Hazen did research there.
(D) It awarded a prize to Hazen and
Brown.
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48
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The word
"both" in line 11 refers to
(A) Hazen and Brown
(B) penicillin and
streptomycin
(C) the Department of
Health laboratories at Albany and New York
(D) double effect
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49
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What substance did Brown and Hazen analyze?
(A) Dirt
(B) Streptomycin
(C) Bacteria
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50
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Who was W. B. Nourse?
(A) A microbiologist
(B) A teacher of
Hazen's
(C) A collector of
fungi
(D) A farmer
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ANSWER KEY
45. B
46. B
47. C
48. A
49. A
50. D
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